Angela K. Pannier, Ph.D.

Biomedical Engineer and Associate Professor
William E. Brooks Engineering Leadership Fellow


Office: 231 L.W. Chase Hall
Phone: (402) 472-0896
Lab Page:



Ph.D. Biological Sciences, Northwestern University
M.S. Biological Systems Engineering, University of Nebraska-Lincoln
B.S. Biological Systems Engineering, University of Nebraska-Lincoln


60% Research
40% Teaching

Research Interests
  • Nonviral Gene Delivery
  • Protein-Cell-Biomaterial Interactions
  • Tissue Engineering
  • Stem Cell Differentiation
Teaching Interests
  • BSEN 317: Introduction to Biomedical Engineering
  • BSEN 416/816: Introduction to Biomaterials
  • BSEN418/818: Tissue Engineering
  • AGEN/BSEN 470/480: Senior Capstone Design I and II
  • BSEN 998: Delivery of Nucleic Acids
Professional Recognition
  • Gamma Sigma Delta (2011)
  • Honorary Member of Black Masque Chapter of Mortar Board (Faculty Inductee, 2011)
  • American Heart Association Scientist Development Grant (2010)
  • Nebrasak EPSCoR First Award (2008)
  • Acta Biomaterialia Author Award (2005)
Selected Publications
Refereed Journal Articles

1. Rodenhausen KB, Schmidt D, Kasputis T, Pannier AK, Schubert E, and Schubert M. 2012. Generalized ellipsometry in-situ quantification of organic adsorbate attachment within slanted columnar thin films. Optics Express. 20(5):5419-28.

2. Othman SF, Curtis ET, Plautz SA, Pannier AK, Butler SD, Xu H. 2012. Magnetic Resonance Elastography monitoring of tissue engineered constructs. NMR in Biomedicine. 25(3):452-63.

3. Sharp AT, Pannier AK, Wysocki BJ, Wysocki TA. 2012. A novel telecommunications-based approach to HIV modeling and simulation. Nano Communication Networks. 3(2): 129-137.

4. Plautz SA, Boanca G, Riethoven J-JM, Pannier AK. 2011. Microarray Analysis of Gene Expression Profiles in Cells Transfected with Nonviral Vectors. Molecular Therapy 19(12):2144-51.

5. Rodenhausen KB, Kasputis T, Pannier AK, Gerasimov JY, Lai RY, Solinsky M, Tiwald TE, Wang H, Sarkar A, Hofmann T, Ianno N, and Schubert M. 2011. Combined optical and acoustical method for determination of thickness and porosity of transparent organic layers below the ultra-thin lm limit. Review of Scientific Instruments. Oct; 82(10):103111.

6. Rodenhausen KB, Duensing BA, Kasputis T, Pannier AK, Hofmann T, Schubert M, Tiwald TE, Solinsky M, and Wagner M. 2011. In-situ monitoring alkanethiol self-assembled monolayer chemisorption with combined spectroscopic ellipsometry and quartz crystal microbalance techniques. Thin Solid Films. 519(9): 2817-2820.

7. Singh D1, Pannier AK, Zempleni J. 2011. Identification of holocarboxylase synthetase chromatin binding sites using the DamID technology. Anal Biochem. 413(1):55-9.

8. Bellis AD, Bernabé BP, Weiss MS, Yarrington ME, Barbolina MV, Pannier AK, Jeruss JS, Broadbelt LJ, Shea LD. 2011. Cellular arrays for large-scale analysis of transcription factor activity. Biotechnol Bioeng. 108(2):395-403.

9. Pannier AK, Wieland JA, Shea LD. 2008. Incorporation of polyethylene glycol into self-assembled monolayers enhances substrate-mediated gene delivery by nonspecifically- bound complexes. Acta Biomat. 4:26-39.

10. Pannier AK, Ariazi EA, Bellis AD, Bengali Z, Jordan VC, Shea LD. 2007. Bioluminescence imaging for assessment and normalization in transfected cell arrays. Biotechnol Bioeng. 98:486-97.

11. Pannier AK, Anderson BC, Shea LD. 2005. Substrate-mediated delivery from self-assembled monolayers: Effect of surface ionization, hydrophilicity, and patterning. Acta Biomat. 1:511-522.

12. Bengali Z, Pannier AK, Segura T, Anderson BC, Jang JH, Mustoe TA, Shea LD. 2005. Gene delivery through cell culture substrate adsorbed DNA complexes. Biotechnol Bioeng. May 5; 90(3):290-302.

13. Pannier AK, Shea LD. 2004. Controlled release systems for DNA delivery. Mol. Ther. 10: 19-26.

 14. Pannier AK, Arora V, Iversen PL, Brand. 2004. Transdermal delivery of phosphorodiamidate Morpholino oligomers across hairless mouse skin. Int. J. Pharm. 275:217-226.

15. Pannier AK, Brand, RM, Jones DD. 2003. Fuzzy modeling of skin permeability coefficients. Pharm. Res. 20: 143-148.

Book Chapters

1. Pannier AK and Segura T. 2012. Surface- and Hydrogel-Mediated Delivery of Nucleic Acid Nanoparticles. In: Ogris M and Oupicky D (eds) Nanotechnology for Nucleic Acid Delivery (in press).


1. Segura T, Shea LD, Pannier AK, Bengali Z, Jang JH, Chung P, and Anderson B. Controlled surface-associated delivery of genes and oligonucleotides. U.S. Patent No. 7,029,697. April 18, 2006.